Poster Presentation Joint Annual Scientific Meeting of the Nutrition Society of NZ and the Nutrition Society of Australia

Postprandial chylomicron metabolism and size distribution is affected by meal oil type (#P26)

Deasy Irawati 1 2 , John CL Mamo 2 , Mario J Soares 2 , Karin M Slivkoff-Clark 2 , Tony P James 2
  1. Faculty of Medicine, Mataram University, West Nusa Tenggara, Indonesia
  2. School of Public Health, Faculty of Health Sciences, Curtin University, Perth, Australia

Aim: To investigate the effect of consumption of different edible oils on postprandial chylomicron size distribution and metabolism in healthy normolipidemic subjects.

Methods: Volunteers received in random order an isocaloric mixed meal containing 40 g of either: palm oil (PO), coconut oil (CO), or rice bran oil (RBO) on 3 occasions. Apolipoprotein (apo) B-48 concentration, a measure of chylomicron particle number, was measured at 0, 4 and 8 hours postprandially in lipoprotein fractions with Svedberg flotation rates (Sf) >400, Sf 20-400 and Sf <20. The trial was registered ACTRN 12614000352606.

Results: Preliminary data indicatethat ~80% of the fasting and postprandial concentrations of apo B-48 is found in the Sf <20 fraction following all test meals. Following consumption of the CO meal a greater proportion of the postprandial apo B-48 response (corrected for baseline levels, incremental area under the curve (IAUC)) were observed in the Sf <20 fractions compared to other oils. However following consumption of the RBO meal a greater postprandial apo B-48 response was observed in all lipoprotein fractions compared with the CO and PO meals. 

Conclusion: We observed that following consumption of all oils the majority of the chylomicrons particles were present in the small dense lipoprotein fraction (Sf <20), however differences exist in the postprandial response following consumption of different edible oils.

Funding source: Curtin University